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The different explanations aren’t mutually exclusive: further research may find that the differences in musculature, blood flow, and the balance of hormones and neurotransmitters all contribute. Exactly why this may be is still unclear, but it could relate to the rise and fall of progesterone levels during the cycle phases. Without that corroboration, they worry that inadequately supported public claims may inadvertently harm women’s recoveries. We found out that his claims are right, and that the content in the book are very effective. They found that injuries during the follicular phase (after menstruation and before ovulation) were less likely to lead to symptoms a month later, while an injury during the luteal phase (after ovulation and before menstruation) resulted in significantly worse outcomes. So, if a head injury occurs during this time, it seems to throw the dopamine signalling off balance in the long term, with potentially important ramifications for those many different brain functions. Dopamine is implicated in many of the brain’s functions that are influenced by concussion—including motivation, mood, memory and concentration—making it a good contender for a potential mechanism.